Video summary
Professor Brian Cox describes the work of William Perkin as he attempted to find a way to make synthetic quinine to treat malaria.
Perkin started with a similar chemical to quinine (aniline, or phenylamine) and tried to oxidise it with potassium dichromate.
He produced a dark precipitate which seemed to stain anything it touched purple.
Purifying this gave him the purple dye mauveine.
This dye became popular after Queen Victoria wore clothes dyed with it.
This discovery initiated a revolution in synthetic chemistry.
Professor Cox reflects that Perkin鈥檚 curiosity and freedom to explore science and unexpected results were essential elements in this important discovery.
This short film is from the 成人快手 series, Science Britannica.
Teacher Notes
This short film could be used to illustrate that not all scientific discoveries are achieved by people finding what they are looking for and that discoveries are more likely when scientists are curious and keen to explore in a methodical way.
This short film will be relevant for teaching chemistry at KS3 and KS4/GCSE and National 4/5 and Higher in Scotland.
This topic appears in OCR, Edexcel, AQA, WJEC KS4/GCSE in England and Wales, CCEA GCSE in Northern Ireland and SQA.
Who was Henry Cavendish? video
Professor Brian Cox introduces Henry Cavendish, the 18th Century scientist who investigated hydrogen, came up with the formula H20 and founded the Royal Institution.
Who was Humphry Davy? video
Brian Cox follows in the footsteps of 19th Century chemist Humphry Davy, recreating one of his explosive experiments that he used to impress the crowds at the Royal Institution.
John Hunter and public engagement in science. video
Brian Cox describes how John Hunter pushed the boundaries of medicine using corpses obtained from grave-robbing and how he set up a museum to open minds about medical research.
Sir Isaac Newton and the scientific method. video
Brian Cox outlines the historical context of the era in which Newton began to be interested in the nature of the visible spectrum obtained using a prism.
John Tyndall and blue skies research. video
Brian Cox describes the work of John Tyndall and his attempts to explain what makes the sky blue and the sunset red.
Targeted research. video
Brian Cox learns about targeted research in the modern pharmaceutical industry and how by focusing only on positive results, it fails to report negative results.
Global warming resistant GM crops. video
Brian Cox outlines the history of the discovery of DNA and how this has led to a controversy over the use of genetic modification in agriculture.